We would like to inform you that the Fertilita Infertility Treatment Center changed location from 18.09.2023. We would like to invite you to Ruda Śląska, Aleja Powstań Śląskich 34 (the building of the Endometriosis Treatment Center)
Candidates for participation in the project will be recruited among women at risk of POF.
The following candidates will be considered for the Project:
The patients will be classified into two groups:
40 patients before anticancer treatment who have a high risk of treatment-induced POF
40 patients with idiopathic POF
Patient group selection:
Recruitment of 80 patients who will give their written informed consent to donate fragments of the ovarian cortex for research purposes.
Group 1: 40 patients prior to anticancer treatment who are at high risk of POF
• diagnosis of cancer in the absence of ovarian involvement;
• serum levels of anti-Müllerian hormone (AMH) ≥1.4 ng/mL
• > 4 antral follicles assessed by ultrasound
• good cancer survival prognosis
Group 2: 40 patients with idiopathic POF
• Serum AMH between 0.1 and 0.7 ng/mL
Expected benefits for patients:
It is expected that this medical experiment will provide its participants with therapeutic benefit in the form of healthy pregnancy, which is currently impossible to achieve in this group of patients.
The use of donor cells will be avoided in these patients
Possible adverse effects of the experiment:
Complications related to endoscopic procedures (laparoscopy),
Complications related to general anaesthesia.
The experimental protocol:
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